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Enabling New DNA-Based Therapy For Anti-Cancer Drug Delivery

Enabling New DNA-Based Therapy For Anti-Cancer Drug Delivery

April 20, 2020

https://engineering.columbia.edu/press-releases/gang-bnl-dna-origami-protection

(Top left) Structure of the octahedral-shaped DNA origami imaged with a transmission electron microscope (scale bar: 50 nanometers); the inset is a schematic of this structure. (Bottom left) Schematic of the two different types of peptoid architectures for the DNA origami coating: brush and block. (Right) Molecular dynamics simulations of the interactions between duplex DNA and peptoid architectures of the brush (top) and block (bottom) type (blue = peptoid backbone, red = DNA binding domain, blue = water-s — Structure of octahedral-shaped DNA Origami

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