Our efforts are focused on establishing experimental methods for creating designed nanomaterial systems through self-organization. We integrate nanoparticles, biomolecules and polymers into unified systems to take advantage of their unique properties, and to exploit the emergent phenomena. Using tailored nano-structures, molecular recognitions, and macromolecular plasticity, we investigate how to build designed nanoscale systems with precise architectures, re-configuration properties, and the ability to react and process energy.